Chapter 1: Cell Structure and Function

 Cell structure and function

Cell theory

1.      Explain the modern theory of cellular organization

2.      State the four main points of the modern theory of cellular organization.

3.      Why are cells called the basic unit of structure and function in living organisms?

4.      How do new cells arise according to the modern theory of cellular organization?

Techniques used in cell biology

5.      Name common techniques used for isolating and examining various cell components.

Magnification and resolution

6.      How does the magnification power of a microscope depend on its lenses?

7.      What is the magnification of a microscope when an objective lens of x40 is used with an eye piece lens of x6?

8.      Differentiate between resolution and magnification

9.      Define magnification and resolution in microscopy.

10.   Why is the resolving power of a microscope important for biologists?

11.   What limits the resolving power of a compound light microscope?

Scientific facts

12.   Which is the oldest accurately dated life form and how old is it?

13.   Name the microorganism that dates back 3500 million years.

Staining

14.   Describe different types of staining techniques in cell biology

15.   Why are staining techniques necessary for observing cells under a microscope?

16.   Differentiate between temporary stains and permanent stains with examples.

17.   Name two temporary stains and their suitable uses.

18.   Which stain is used to observe DNA in a permanently fixed cell?

19.   Match the following stains with their final colours:(i) Acetocarmine (ii) Safranin (iii) Fast green (iv) Lugol’s iodine

20.   Which permanent stain is suitable for staining nuclei, different spores, and bacteria?

Centrifugation

21.   Explain the principle and process of differential centrifugation

22.   Define differential centrifugation and explain its main purpose in cell biology.

23.   What happens to larger and denser organelles during centrifugation compared to smaller and lighter ones?

24.   Describe the steps involved in the differential centrifugation process.

25.   Why must tissue be homogenized before centrifugation?

Tissue culture

26.   Explain the concept of tissue culture

27.   Define tissue culture and explain its basic purpose.

28.   Why are plant tissues often used in tissue culture experiments?

29.   What is meant by “genotypically identical cells” in the context of tissue culture?

Plant tissue culture

30.   List the materials and equipment required for plant tissue culture.

31.   Explain why sterilization of the culture medium is important.

32.   Describe the main steps involved in plant tissue culture.

33.   What is the role of plant growth regulators in tissue culture?

 

Chromatography

34.   Define chromatography and state its main purpose in biology.

35.   What is the stationary phase in paper chromatography?

36.   Give two examples of substances that can be separated using chromatography.

37.   Why do different molecules travel at different speeds during chromatography?

38.   How is the chromatogram obtained in paper chromatography?

Electrophoresis

39.   Define electrophoresis and explain its basic principle.

40.   Why do different molecules move at different rates during electrophoresis?

41.   Name two biological molecules that can be separated using electrophoresis.

Microdissection and micrometry

42.   Describe the uses of a microscope in microdissection and micrometry

43.   What is microdissection and how is it performed?

44.   Give two uses of microdissection in cell biology.

45.   Define micrometry and explain its importance in measuring microscopic objects.

46.   Which type of microscope is required for micrometry?

47.   Explain how the ocular and stage micrometers are used together to measure cell size.

48.   Apply micrometry in biological measurement

49.   What is micrometry and why is it important in biology?

50.   How is the size of a microscopic object calculated using micrometry?

Cell wall

51.   Describe the structure and functions of the cell wall

52.   Name the three fundamental layers of the cell wall.

53.   What is the primary chemical component of the cell wall?

54.   Define the primary wall, secondary wall, and middle lamella.

55.   State two functions of the cell wall in plant cells.

56.   What is the role of the middle lamella in plant tissue?

57.   Mention two uses of cellulose in daily life.

Plasma membrane

58.   Explain the structure and role of the plasma membrane

59.   Describe Fluid Mosaic Model of the plasma membrane?

60.   What is the percentage composition of proteins and lipids in the cell membrane?

61.   Describe the arrangement of proteins and lipids in the plasma membrane according to the Fluid Mosaic Model.

62.   What is meant by “selectively permeable membrane”?

63.   Give two functions of proteins present in the plasma membrane.

64.   How do glycoproteins and glycolipids contribute to cell membrane function?

65.   Explain the role of membrane carbohydrates, glycolipids, and glycoproteins

66.   What are glycolipids and glycoproteins, and where are they found in the plasma membrane?

67.   State two functions of glycolipids in the cell membrane.

68.   How do glycoproteins help in cell-to-cell recognition?

69.   Why are glycolipids and glycoproteins called “cell surface markers”?

70.   Who first proposed the concept of a lipid bilayer and in which year?

Cytoplasm

71.   Describe the structure and functions of cytoplasm

72.   10. Define cytoplasm and name its major components.

73.   11. What is cytosol, and what percentage of water does it contain?

74.   12. List at least four organelles suspended in the cytosol.

75.   3. Explain why cytosol is described as a colloidal solution.

76.   Give three functions of cytoplasm in cell activities.

77.   How does cytoplasm contribute to the movement of materials within a cell?

78.   Define cytoplasmic organelles and give two example.

Endoplasmic reticulum

79.   Describe the structure and function of the endoplasmic reticulum (ER).

80.   Differentiate between rough ER (RER) and smooth ER (SER).

81.   What is the role of ribosomes attached to the RER?

82.   State two functions of SER in the cell.

Ribosomes

83.   Explain the structure and function of ribosomes

84.   What are ribosomes composed of?

85.   Differentiate between the 70S ribosome and the 80S ribosome in terms of size and location.

86.   Name the two subunits of a ribosome and their respective sizes in eukaryotic cells.

87.   What is a polysome and what is its role in protein synthesis?

88.   Why are ribosomes called “protein factories” of the cell?

89.   Who discovered ribosomes and in which year?

90.   Which scientist coined the term “ribosome”?

Golgi apparatus

91.   Describe the structure and functions of the Golgi apparatus

92.   Who discovered the Golgi apparatus and in which year?

93.   What is the structure of the Golgi apparatus composed of?

94.   State two main functions of the Golgi apparatus in the cell.

95.   How does the Golgi apparatus modify and package proteins?

96.   What is the relationship between the ER and the Golgi apparatus?

Lysosomes

97.   Explain the structure and functions of lysosomes

98.   Define lysosomes and state their function in the cell.

99.   What are primary lysosomes and how do they form?

100.  Differentiate between primary and secondary lysosomes.

101.     Why are lysosomes called “suicide bags” of the cell?

102.     Name two enzymes commonly found in lysosomes.

 

Peroxisomes

103.     Describe peroxisomes and their role

104.     What are peroxisomes and what is their typical size?

105.     Which enzyme present in peroxisomes breaks down hydrogen peroxide?

106.     State two functions of peroxisomes in animal cells.

107.     How do peroxisomes protect cells from oxidative damage?

Cytoskeleton

108.     Describe the structure and function of the cytoskeleton

109.     Define cytoskeleton and name its three main components.

110.     Who discovered the cytoskeleton and in which year?

111.     What is the function of microtubules in a cell?

112.     Differentiate between microtubules, microfilaments, and intermediate filaments.

113.     How do microfilaments contribute to cell movement?

Centriole

114.     Explain the role and structure of centrioles

115.     What are centrioles and in which types of cells are they found?

116.     Describe the structure of a centriole.

117.     What is the role of centrioles in cell division?

118.     How are microtubules arranged in a centriole?

119.     State two functions of centrioles apart from their role in mitosis.

Cilia and flagella

120.     Describe the structure and function of cilia and flagella

121.     What are cilia and flagella, and how do they differ in size and number per cell?

122.     Describe the structure of a cilium with reference to its microtubule arrangement.

123.     What is the 9 + 2 arrangement found in cilia and flagella?

124.     How are cilia and flagella anchored to the cell?

125.     Mention two functions of cilia and flagella in cells.

Mitochondria

126.     Explain the structure and role of mitochondria

127.     What is the main function of mitochondria in a cell?

128.     Describe the structure of a mitochondrion, including its membranes and cristae.

129.     Why are mitochondria called the “powerhouses” of the cell?

130.     What is the significance of mitochondrial DNA and ribosomes?

131.     How does the inner membrane of mitochondria assist in ATP production?

Plastids

132.     Identify the types and functions of plastids

133.     What are plastids and in which type of cells are they found?

134.     List the three main types of plastids and their primary functions.

135.     What is the role of chlorophyll in chloroplasts?

136.     How does the structure of chloroplasts support photosynthesis?

137.     Differentiate between chloroplasts, chromoplasts, and leucoplasts.

138.     Describe the structure and function of chloroplasts and other plastids

139.     What are thylakoids, and how are they arranged in a chloroplast?

140.     Define stroma and list its main components.

141.     How do chloroplasts resemble mitochondria in structure?

142.     What pigment is present in chromoplasts, and what is its function?

143.     Where are leucoplasts commonly found, and what is their role?

144.     Differentiate between types of plastids

145.     Compare the functions of chloroplasts, chromoplasts, and leucoplasts.

146.     Why are chromoplasts important in pollination and seed dispersal?

147.     Which plastid type is involved in starch storage?

148.     How does pigment composition vary among the three types of plastids?

Nucleus

149.     Explain the structure and function of the nucleus

150.     Who discovered the nucleus, and in which year?

151.     Name the three main components of the nucleus.

152.     Describe the structure and function of the nuclear membrane.

153.     What is the role of nuclear pores?

154.     Explain the function of the nucleolus in protein synthesis.

155.     Explain the concept of diploid and haploid numbers of chromosomes

156.     What is meant by diploid (2n) and haploid (n) chromosome numbers?

157.     Why is it important for gametes to have a haploid number of chromosomes?

158.     Give an example of an organism with a diploid number of 46 chromosomes.

159.     How many chromosomes are present in a human sperm cell?

160.     Why do chromosome numbers remain constant in a species from generation to generation?

Compare prokaryotic and eukaryotic cells

161.     Compare prokaryotic and eukaryotic cells

162.     State one main difference between the genetic material of prokaryotes and eukaryotes.

163.     How is the DNA of prokaryotic cells arranged?

164.     What is meant by the term “nucleoid”?

165.     Why do prokaryotic cells lack a nuclear membrane?

166.     Give an example of an organism with a prokaryotic cell structure.

Structure of a bacterial cell

167.     Describe the structure of a bacterial cell

168.     What is the composition of the bacterial cell wall?

169.     What is the role of peptidoglycan in bacteria?

170.     Which structures protect bacterial cells from osmotic lysis?

171.     How do bacterial ribosomes differ from eukaryotic ribosomes?

172.     What is the function of the bacterial cell membrane?

173.     What is the function of the bacterial capsule?

174.     How does the bacterial flagellum help the cell?

175.     Where is the nucleoid located in a bacterial cell?

176.     What is the role of plasmids in bacteria?

177.     Define conjugation in bacteria.

178.     How is DNA transferred from one bacterium to another during conjugation?

179.     What happens during transformation in bacteria?

180.     Explain the role of bacteriophages in transduction.

181.     Differentiate between transformation and transduction.

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